Only software I use is Logic Pro 9 and it's typically just used as a bad ass recorder.
Can't figure out Live to save my gramma's life.
Pro Tools is insanely uninspiring to me after using it for a year straight at school... /wrists
Any time the software instruments are used I am sampling them into the MPC or OP-1, and keep it like that for sake of simplicity. No MIDI sequencing needed.
Everything I've been doing lately has been recorded to tape so I'm now finding out a whole new workflow between digital editing and analogue recording. Pretty fun thus far.